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Researchers discover that a protein that facilitates DNA repair may enhance chemotherapy

Binding of PrimPol to ICL lesions in DNA. PrimPol protein (red) is distributed between the nucleus (blue) and cytoplasm of osteosarcoma cells (left). In the presence of ICL lesions, PrimPol quickly binds to damaged DNA to facilitate its repair (right). Credit: CNIO Chemotherapy kills tumor cells by causing damage to them. One of the most effective ways of causing damage ...

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Bed sharing not as critical as claimed

Credit: Pixabay/CC0 Public Domain New research led by the University of Kent has found that there is no link between bed sharing, infant-mother attachment, and infant behavioral outcomes. Contrary to previous beliefs that bed sharing is beneficial (or even required) for babies to develop a secure attachment style and for mothers to develop a strong bond to their baby, researchers ...

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Rates of reamputation high in patients with diabetes

(HealthDay)—Nearly four in 10 patients with diabetes who have undergone initial amputations secondary to diabetes will have a reamputation within five years, according to a review published online June 10 in BMJ Open Diabetes Research & Care. Rongqi Liu, from Podimetrics Inc. in Somerville, Massachusetts, and colleagues conducted a systematic literature review to assess trends in reamputation rates in people ...

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Family history doubles asthma risk for preschoolers

(HealthDay)—Children with a family history of asthma have more than twofold higher rates of asthma through age 4 years, according to a study published online May 17 in JAMA Pediatrics. Christine Cole Johnson, Ph.D., M.P.H., from the Henry Ford Health System in Detroit, and colleagues used data from the Environmental Influences on Child Health Outcomes consortium (May 1, 1980, through ...

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US COVID-19 deaths hit 600,000, equal to yearly cancer toll

In this Jan. 9, 2021 file photo, transporters Miguel Lopez, right, Noe Meza prepare to move a body of a COVID-19 victim to a morgue at Providence Holy Cross Medical Center in the Mission Hills section of Los Angeles. The U.S. death toll from COVID-19 has topped 600,000, even as the vaccination drive has drastically slashed daily cases and deaths ...

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Fears breast cancer progress could stall due to COVID-19 backlog

Credit: Pixabay/CC0 Public Domain Around 10,600 fewer breast cancer patients have started treatment in the last year in England. Breast cancer deaths reached an all-time low before the pandemic, but experts fear these new stats show that this hard-won progress could slow. The charity estimates around 38,000 fewer people started treatment for all cancer types in England. And breast cancer ...

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Integrating multiple models provides best control of pandemic as states reopen

Credit: Pixabay/CC0 Public Domain Leaders deciding how to contain COVID-19 most effectively should use multiple different mathematical models together in policy design instead of just one, according to new research. A study co-authored by Ross School of Business professors Hyun-Soo Ahn and John Silberholz proposes a practical way to combine multiple COVID-19 models and generate the best guidance for individual ...

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